Mostrando las entradas con la etiqueta HIV. Mostrar todas las entradas
Mostrando las entradas con la etiqueta HIV. Mostrar todas las entradas

08 mayo, 2013

Universal screening for hearing loss in newborns: US Preventive Services Task Force recommendation statement

Pediatrics. 2008 Jul;122(1):143-8. doi: 10.1542/peds.2007-2210.

Universal screening for hearing loss in newborns: US Preventive Services Task Force recommendation statement.


Source

US Preventive Services Task Force, Agency for Healthcare Research and Quality, Rockville, MD 20850, USA. uspstf@ahrq.hhs.gov

Abstract

DESCRIPTION:

This is the 2008 update of the 2001 US Preventive Services Task Force recommendation on universal newborn hearing screening.

METHODS:

The US Preventive Services Task Force weighed the benefits and harms of universal newborn hearing screening, incorporating new evidence addressing gaps identified in the 2001 US Preventive Services Task Force recommendation statement. Published literature on this topic was identified (by using Medline and Cochrane databases) and systematically reviewed.

RECOMMENDATION:

Screen for hearing loss in all newborn infants (B recommendation).

Comment in

Pediatricians and the US Preventive Services Task Force: a natural partnership to enhance the health of children. [Pediatrics. 2008]

02 mayo, 2013

U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for coronary heart disease (CHD).

38 Double Outlet Right Ventricle with ASD, VSD...
38 Double Outlet Right Ventricle with ASD, VSD, bicuspid aortic (Photo credit: HeartBabyHome)
Description:
Update of the 2004 U.S. Preventive Services Task
Force (USPSTF) recommendation statement on screening for coro-
nary heart disease (CHD).
Methods:
The USPSTF reviewed new evidence on the benefits of
screening with electrocardiography (ECG) in asymptomatic adults to
reduce the risk for CHD events versus not screening, the effect of
identifying high-risk persons on treatment to reduce risk, the accu-
racy of stratifying individuals into risk categories, and the harms of
screening.
Recommendations:
The USPSTF recommends against screening
with resting or exercise ECG for the prediction of CHD events
in asymptomatic adults at low risk for CHD events (D
recommendation).
The USPSTF concludes that the current evidence is insufficient to
assess the balance of benefits and harms of screening with resting
or exercise ECG for the prediction of CHD events in asymptomatic
adults at intermediate or high risk for CHD events (I statement).
Ann Intern Med.
2012;157:512-518.
www.annals.org
For author affiliation, see end of text.
* For a list of the members of the USPSTF, see the
Appendix
(available at
www.annals.org).
This article was published at www.annals.org on 31 July 2012.

30 abril, 2013

Guidelines from the USPTF: HIV Screening

English: Vectorized version of graph showing H...
English: Vectorized version of graph showing HIV viral load in relation to CD4+ lymphocyte count (Photo credit: Wikipedia)

Screening for HIV

U.S. Preventive Services Task Force Recommendation Statement

Release Date: April 2013
Clinical Summary : Recomendation A.


This article was first published in Annals of Internal Medicine (Ann Intern Med 2013;30 Apr). Select for copyright and source information.

Contents

Summary of Recommendations and Evidence Rationale Clinical Considerations Other Considerations Discussion Update of Previous Recommendation Recommendations of Others Members of the Task Force References
Task Force Ratings Strength of Recommendations and Quality of Evidence

Summary of Recommendations and Evidence

The USPSTF recommends that clinicians screen for HIV infection in adolescents and adults aged 15 to 65 years. Younger adolescents and older adults who are at increased risk should also be screened (A recommendation).
Go to the Clinical Considerations for more information about screening intervals.
The USPSTF recommends that clinicians screen all pregnant women for HIV, including those who present in labor who are untested and whose HIV status is unknown. (A recommendation)

Rationale

Importance

An estimated 1.2 million persons in the United States are currently living with HIV infection, and the annual incidence of the disease is approximately 50,000 cases. Since the first cases of AIDS were reported in 1981, more than 1.1 million persons have been diagnosed and nearly 595,000 have died from the condition. Approximately 20% to 25% of individuals living with HIV infection are unaware of their positive status.

Detection

The USPSTF found convincing evidence that conventional and rapid HIV antibody tests are highly accurate in diagnosing HIV infection.

Benefits of Detection and Early Intervention

The USPSTF found convincing evidence that identification and treatment of HIV infection is associated with a markedly reduced risk for progression to AIDS, AIDS-related events, and death in individuals with immunologically advanced disease (defined as a CD4 count <0 .200="" 10="" sup="">9
cells/L). Adequate evidence shows that initiating combined antiretroviral therapy (ART) earlier (that is, at CD4 counts between 0.200 and 0.500 × 109 cells/L)—when individuals are more likely to be asymptomatic and detected by screening rather than clinical presentation—is also associated with reduced risk for AIDS-related events or death. The USPSTF found convincing evidence that the use of ART is associated with a substantially decreased risk for transmission from HIV-positive persons to uninfected heterosexual partners. Convincing evidence also shows that identification and treatment of HIV-positive pregnant women dramatically reduces rates of mother-to-child transmission. The overall benefits of screening for HIV infection in adolescents, adults, and pregnant women are substantial.

Harms of Detection and Early Intervention

The USPSTF found convincing evidence that individual antiretroviral drugs, drug classes, and combinations are all associated with short-term adverse events; however, many of these events are transient or self-limited, and effective alternatives can often be found. Although the long-term use of certain antiretroviral drugs may be associated with increased risk for cardiovascular and other adverse events, the magnitude of risk seems to be small. The overall harms of screening for and treatment of HIV infection in adolescents, adults, and pregnant women are small.

USPSTF Assessment

The USPSTF concludes with high certainty that the net benefit of screening for HIV infection in adolescents, adults, and pregnant women is substantial. 

23 octubre, 2012

Le origine del mal ( AIDS)

English: The Red ribbon is a symbol for solida...
English: The Red ribbon is a symbol for solidarity with HIV-positive people and those living with AIDS. Français : Le Ruban rouge, symbole de la solidarité avec les personnes séro-positives. (Photo credit: Wikipedia)
Most of the time, we are looking for new ways the real world.......science became as religion everytime we believe in only another important people says for us.....is time to think for ourwelves, is time of changes, a new order world is building another war to increase the production of weapons. Not all is medicine here.......but sometime is good to know that we can think by ourselves....that is an interesting documental, in italian traduced to spanish about the AIDS origin.....no really matters the origin many people think........just look, and think for yourself.


Este documental de origen italiano (2007) , se refiere a las distintas teorias acerca del origen del SIDA. Es un documental teatralizado, donde el eje de la discusion deja de ser el origen mismo del SIDA, para pasar a cuestionar las distintas razones por las que esta discusion parece no ser importante para la ciencia. De como multiples teorias fueron rechazadas sin ningun argumento mas que el criterio de autoridad, o la censura explicita de revistas como Science. La ciencia no trata de respuestas, sino de la busqueda de las mismas, y en el camino de la ciencia verdadera, nos encontramos con mas preguntas que respuestas. La ciencia nace justamente de nuestra ignorancia, de nuestra inquietud por conocer la verdad. Pero parece que cual la epoca medieval, donde la ciencia era propiedad eclesiastica, hoy tambien se ha transformado en una religion, dominada por otros intereses muchos mas oscuros. Y al fin de cuentas, las religiones se transforman en mas sinceras, cuando piden a sus creyentes justamente eso: fe . Y la ciencia de hoy se esta transformando cada vez mas en una cuestion de fe, con modelos matematicos que dificilmente puedan explicar lo maravilloso de la vida humana en la tierra, con sus caracteristicas biologicas, psicologicas, sociales, culturales, y en el contexto de un medio ambiente, que por cierto ha dejado de respetar. Vale la pena, y la alegria, el ver este documental. Y que lo disfruten como yo.




26 septiembre, 2011

Routine HIV Screening - HIV: CDC x USPSTF


Após acabar de publicar as recomendações do US Preventive Services Task Force sobre ECG (não triar), acabo de ler o ahead of print do New England Journal of Medicine que discute justamente as recomendações da Task Force (não triar universalmente HIV) contra as recomendações do Centers for Disease Control (triagem universal).

O artigo faz um apanhado interessante da discussão entre as duas entidades acerca da análise das mesmas evidências científicas, destacando que, a despeito das evidências não serem as mesmas, a análise de diferentes pesquisadores (cochranistas x especialistas).

Os dois grupos debatem sob diversas óticas, incluindo a da economia da saúde (de custo-benefício e custo-efetividade), a do risco relacionado a triagem e da responsabilidade das próprias entidades em se obrigarem a fazer ou não recomendações.

As referências são bastante interessantes, e a ótica do autor deste artigo traduz a panacéia que existe em torno da Medicina Baseada em Evidências.

Lembrando que só recentemente o atual presidente Barack Obama suspendeu a obrigatoriedade do exame de HIV para imigrantes, uma exigência da administração anterior, é importante entender o contexto em que se desenvolvem estas recomendações.

Leia o artigo do NEJM:




Publicado originalmente por Leonardo C M Savassi

19 junio, 2011

Documental: el origen del SIDA

Fin de semana largo en Argentina, y dia del padre. Asi que quien quiera ver una peli, aqui va una. En realidad siendo domingo no queria que se trate de medicina, pero en este caso es sobre el origen del sida, son dos videos, uno teatralizado y el otro documental. Obviamente me gusta mas el teatralizado, no dudo que se van a entretener más. Que los disfruten y se esperan comentarios. http://la-baulera.blogspot.com/2011/06/documental-el-origen-del-sida.html

06 octubre, 2008

Las dudas sobre la relacion del SIDA y el VIH

Damos como verdad aceptada la relacion entre SIDA y la infeccion por VIH. Para algunos investigadores, los menos, esto ya constituye un dogma de fe, algo que atenta contra los principios de la ciencia. Ciertamente el SIDA existe. Pero es el VIH la causa unica del mismo? Los metodos diagnosticos parecen no ser los adecuados, y menos aun los criterios de su interpretacion. Kits de laboratorios que por cierto tambien son producidos por laboratorios que tambien producen medicamentos contra este problema. Africa esta muriendo, pero esta muriendo por VIH, o muere de hambre? Y los datos en paises desarrollados muestran una menor mortalidad por SIDA de la que inicialmente se reporto en EE.UU. Demasiadas dudas. Dudas que si bien para quienes vean este video pueden resultar provocadoras, no lo es si pensamos que solo con la duda podremos obtener la verdad. Quizas sea este el mayor valor que tiene este video.