AVC | Critically appraised articles
:
Purssell E. Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone. Arch Dis Child. 2011;96:1175-9. D.O.I.: 10.1136/archdischild-2011-300424.
Reviewers:
Llerena Santa Cruz E1, Guarch Ibáñez B2, Buñuel Álvarez JC3
1 Hospital Universitario Dr. Josep Trueta. Girona (España).
2 Hospital Universitario Dr. Josep Trueta. Girona (España).
3 Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona (España). Correspondence: Enrique Llerena Santa Cruz. Email: santum7@yahoo.com
Palabras clave: terapia combinada; paracetamol; ibuprofeno; fiebre; esquema de medicación
Keywords: combined modality therapy; acetaminophen; ibuprofen; fever; drug administration schedule
Reception date: 03/02/2012 Acceptance date: 16/02/2012 Publication date: 22/02/2012
Full Article in PDF and Spanish
http://ubuntuone.com/12dp7AVqkOznLuZymMAxjg
How to citate this article
Llerena Santa Cruz E, Guarch Ibáñez B, Buñuel Álvarez JC. No existen pruebas suficientes que avalen el uso de ibuprofeno y paracetamol combinados para el tratamiento de la fiebre. Evid Pediatr. 2012;8:18.Bibliography
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- Esparza Olcina MJ. Eficacia y seguridad de ibuprofeno y paracetamol en niños y adultos: metanaanálisis y revisión cualitativa. Evid Pediatr. 2011;7:98.
- Prymula R, Siegrist CA, Chlibek R, Zemlickova H, Vackova M, Smetana J et al. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials. Lancet. 2009;374:1339-50.
